Evolve A Cell Wiki

Evolve a Cell Tier List

Rankings for every part and mutation, based on how they performed across the gameplay we reviewed. Speed and sustain sit at the top; anything that only works in one situation sits lower.

Editor's take

This is our opinion, built from watching real runs. Tap any part for the reasoning and the footage. Last checked against the game update of October 13, 2026.

Parts

Mutations

  • ABitterPlayers who eat you get half the DNA and feel sick.
  • SReinforced MembraneDrills and tentacle whips hurt you 50% less.
  • CShallows BornSwim 10% faster in the shallows.

Why these rankings

Speed is the top stat. Every death we tracked involved something faster. Jets and Fins are S-tier because they help you catch prey and escape hunters at the same time.

Drill and Feeding Tube go together. The drill keeps damaging while you push; the tube eats whatever is left, plants included. That combination carried a run all the way to the Colossus.

Leech Mouth is the only healing mouth. In long fights against same-size cells, sustain decides the winner.

Poison drops off. It deletes tiny cells but barely scratches big ones, so it sits at B despite feeling strong early.

Disagree? Read the longer argument, then go test it.